Recombinant Human TIGAR
Product Sizes
25 µg
£528.00
32-5087-25UG
About this Product
- SKU:
- 32-5087
- Additional Names:
- Fructose-2;6-bisphosphatase TIGAR||TP53-induced glycolysis and apoptosis regulator||TIGAR||C12orf5.
- Extra Details:
- Source : Escherichia Coli. TIGAR Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 270 amino acids and having a molecular mass of 30.1kDa. The TIGAR is purified by proprietary chromatographic techniques. TIGAR is a p53-inducible enzyme which catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is an influential activator of 6-phosphofructose-1 kinase (the rate limiting enzyme of glycolysis). By lowering the intracellular level of F-2-6-BP; TIGAR expression leads to increased glucose processing through the pentose phosphate pathway; the main cellular source for NADPH.
- Purification:
- Greater than 95.0% as determined by: (a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized TIGAR stable at room temperature for 3 weeks; should be stored desiccated below -18C. Upon reconstitution TIGAR should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
