Recombinant Human TRAF-Interacting Protein with Forkhead-Associated Domain
Product Sizes
10 µg
£528.00
32-5086-10UG
About this Product
- SKU:
- 32-5086
- Additional Names:
- TRAF-interacting protein with FHA domain-containing protein A||Putative MAPK-activating protein PM14||Putative NF-kappa-B-activating protein 20||TRAF2-binding protein||TIFA||T2BP||T6BP||TIFAA.
- Extra Details:
- Source : Escherichia Coli. TIFA Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 208 amino acids (1-184 a.a.) and having a molecular mass of 24kDa.TIFA is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TRAF-interacting protein with FHA domain-containing protein A (TIFA) is an adapter protein that mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation; triggering the downstream activation of NF-kappa-B and AP-1 pathways. The TIFA protein stimulates the oligomerization and polyubiquitination of TRAF6; leading to the activation of TAK1 and IKK through a proteasome-independent mechanism.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
