Recombinant Human Tissue Factor Pathway Inhibitor
Product Sizes
20 µg
£528.00
32-5063-20UG
About this Product
- SKU:
- 32-5063
- Additional Names:
- Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor)||Extrinsic Pathway Inhibitor||Tissue Factor Pathway Inhibitor||anti-convertin||TFPI1||EPI||LACI||TFI.
- Extra Details:
- Source : Escherichia Coli. TFPI Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 299 amino acids (29-304) and having a molecular mass of 34.3kDa.TFPI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TFPI is a protease inhibitor which controls the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process starts with the creation of a factor VIIa-TF complex; that proteolytically triggers additional proteases (factors IX and X) and eventually results in a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly located in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. A number of alternatively spliced transcript variants of this gene have are known; however the full-length nature of several of these variants were not yet established.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Biomaterials:Tissues
- Manufacturer's Data Sheet:1.jpg
