Recombinant Human Transcription Elongation Factor A (SII)- 1
Product Sizes
20 µg
£528.00
32-5044-20UG
About this Product
- SKU:
- 32-5044
- Additional Names:
- Transcription elongation factor A (SII) 1||Transcription elongation factor TFIIS.o||TCEA||GTF2S||SII||TF2S.
- Extra Details:
- Source : E.coli. TCEA1 Human Recombinant produced in E. coli is a single polypeptide chain containing 325 amino acids (1-301) and having a molecular mass of 36.5kDa.TCEA1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TCEA1 is a member of the TFS-II family. TCEA1 binds to Pol II and operates to cleave the emerging transcript; thus unlocking the complex and permitting transcription to continue. TCEA1 is localized to the nucleus and holds three independently-folding domains that are essential for accurate binding to Pol II. The arresting sites in are able to trap a certain segment of elongating RNA polymerases that goes through; causing in a locked ternary complex. Cleavage of the emerging transcript by S-II enables the renewal of elongation from the new 3'-terminus.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
