Recombinant Human Small Ubiquitin-Related Modifier 2
Product Sizes
50 µg
£528.00
32-5008-50UG
About this Product
- SKU:
- 32-5008
- Additional Names:
- Small ubiquitin-related modifier 2||SUMO-2||Ubiquitin-like protein SMT3B||SMT3 homolog 2||Sentrin-2||HSMT3||SUMO-3||SUMO2||SMT3B||SMT3H2||MGC117191.
- Extra Details:
- Source : Escherichia Coli. SUMO2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 93 amino acids and having a molecular mass of 10.6 kDa.The SUMO-2 is purified by proprietary chromatographic techniques. Small Ubiquitin-like Modifiers (SUMOs) are a family of small; related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. Unlike ubiquitination; which targets proteins for degradation; sumoylation participates in a number of cellular processes; such as nuclear transport; transcriptional regulation; apoptosis; and protein stability. All SUMO proteins share the conserved ubiquitin domain and the C-terminal diglycine cleavage/attachment site. Human SUMO2; also known as Sentrin2 and SMT3B is synthesized as a 95 amino acid (aa); 11 kDa propeptide that contains a two aa C-terminal prosegment; and an 18 aa N-terminal protein interacting region (aa 33 -50). Following prosegment cleavage; the C-terminal glycine is enzymatically attached to a lysine on a target protein. Human SUMO2 shares 100% sequence identity to SUMO-2 from mouse. SUMO2 also has very high sequence homology to SUMO3 and SUMO4; 86 % and 85%; respectively. SUMO2 shares only 44% sequence identity to SUMO1.
- Purification:
- Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Can be stored at +4C for 1 week. For long term storage ; below -20C. Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
