Recombinant Human Sequestosome 1
Product Sizes
25 µg
£528.00
32-4953-25UG
About this Product
- SKU:
- 32-4953
- Additional Names:
- A170||OSIL||p60||p62||p62B||PDB3||ZIP3||EBIAP||ORCA||OSIL||SQSTM1.
- Extra Details:
- Source : Escherichia Coli. SQSTM1 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 264 amino acids (1-356 a.a.) and having a molecular mass of 39.7 kDa. SQSTM1 protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography. SQSTM1 is an adapter protein which binds ubiquitin and mediates the activation of NFKB1 by TNF-a; NGF and IL-1. SQSTM1 is involved in titin/TTN downstream signaling in muscle cells. SQSTM1 controls signaling cascades through ubiquitination. SQSTM1 participates in cell differentiation; apoptosis; immune response and regulation of K(+) channels. Mutations in UBA domain of the SQSTM1 protein cause Paget's disease because the UBA is essential for aggregate sequestration and cell survival.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
