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Recombinant Human SPRY Domain-Containing SOCS Cox Protein 2

Product Sizes
20 µg
£528.00
32-4952-20UG
About this Product
SKU:
32-4952
Additional Names:
SPRY domain-containing SOCS box protein 2||SSB-2||Gene-rich cluster protein C9||SPSB2||GRCC9||SSB2||GRCC9.
Extra Details:
Source : Escherichia Coli. SPSB2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 287 amino acids (1-263 a.a) and having a molecular mass of 31.2kDa.SPSB2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. SPRY Domain-Containing SOCS Cox Protein 2 (SPSB2) belongs to a suppressor of cytokine signaling (SOCS) family; and is a member of the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. SPSB2 is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. SPSB2 is apparent substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and ensuing proteasomal degradation of target proteins.
Purification:
Greater than 85.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg