Recombinant Human Sclerostin Domain Containing 1
Product Sizes
20 µg
£528.00
32-4923-20UG
About this Product
- SKU:
- 32-4923
- Additional Names:
- Sclerostin domain-containing protein 1||Ectodermal BMP inhibitor||Ectodin||Uterine sensitization-associated gene 1 protein||USAG-1||SOSTDC1||USAG1||CDA019.
- Extra Details:
- Source : Escherichia Coli. SOSTDC1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 206 amino acids (24-206 a.a) and having a molecular mass of 23kDa.SOSTDC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Sclerostin Domain Containing 1 (SOSTDC1) belongs to the sclerostin family and an N-glycosylated; secreted protein with a C-terminal cystine knot-like domain. The SOSTDC1 protein acts as a bone morphogenetic protein (BMP) antagonist. Specifically; SOSTDC1 directly associates with BMPs; prohibiting them from binding their receptors; thus regulating BMP signaling throughout cellular proliferation; differentiation; and programmed cell death. SOSTDC1 may also be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and hinders TGF-beta signaling. In addition; SOSTDC1 directly antagonizes the activity of BMP2; BMP4; BMP6 and BMP7 in a dose-dependent manner.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
