Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide A
Product Sizes
10 µg
£528.00
32-4895-10UG
About this Product
- SKU:
- 32-4895
- Additional Names:
- U1 small nuclear ribonucleoprotein A||U1 snRNP A||U1-A||U1A||SNRPA||Mud1.
- Extra Details:
- Source : Sf9 insect cells. SNRPA Human Recombinant produced in SF9 is a glycosylated; polypeptide chain having a calculated molecular mass of 32;102 Dalton. SNRPA is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques. SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein; which binds the 5' splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and is involved in the coupling of splicing and polyadenylation. SNRPA binds stem loop II of U1 snRNA. SNRPA is the first snRNP to interact with pre-mRNA. This interaction is vital for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
