Recombinant Human Gamma-Synuclein
Product Sizes
50 µg
£528.00
32-4889-50UG
About this Product
- SKU:
- 32-4889
- Additional Names:
- Gamma-synuclein||Persyn||Breast cancer-specific gene 1 protein||Synoretin||SR||SNCG||BCSG1||PERSYN||PRSN||g-Synuclein.
- Extra Details:
- Source : Escherichia Coli. g-Synuclein Human Recombinant produced in E.Coli is a single;non-glycosylated polypeptide chain containing 127 amino acids and having a molecular mass of 13;300 Dalton. The protein coding region of g-synuclein was amplified by RT-PCR and cloned into an E.coli expression vector. g-synuclein was overexpressed in E. coli and purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques. g-synuclein(Originally known as a breast cancer specific gene product; BCSG1) is an acidic neuronal protein of 127 amino acids. Gamma-Synuclein is a member of the Synuclein protein family; which is believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of Gamma-Synuclein have been found in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Synuclein-Gamma is found mostly in the peripheral nervous system (in primary sensory neurons; sympathetic neurons; and motor neurons) and retina. SNCG is also identified in the brain; ovarian tumors; and in the olfactory epithelium. SNCG expression in breast tumors is a marker for tumor progression. A modification in the expression of gamma-synuclein has been detected in the retina of Alzheimer's patients.
- Purification:
- Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
