Recombinant Human Alpha-Synuclein Delta-NAC
Product Sizes
50 µg
£528.00
32-4885-50UG
About this Product
- SKU:
- 32-4885
- Additional Names:
- Alpha-synuclein||Non-A beta component of AD amyloid||Non-A4 component of amyloid precursor||NACP||PARK1||PARK4||MGC110988||a-Synuclein||SNCA.
- Extra Details:
- Source : Escherichia Coli. A-Synuclein Delta-NAC Human Recombinant which is a deletion mutant of the a-synuclein that lacks the NAC region (amino acid 61-95); produced in E.Coli is a single; non-glycosylated polypeptide chain of 111 amino acids having a molecular mass of 11.9kDa (molecular size on SDS-PAGE will appear higher); with 6 amino acids added as a linker. The Recombinant Human a-Synuclein Delta-NAC is purified by proprietary chromatographic techniques. a-Synuclein (amino acids 1-140); an acidic neuronal protein of 140 amino acids; is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. a-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders; and more recently; to be an important regulatory component of vesicular transport in neuronal cells. Moreover; recent studies have shown that a-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140).
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
