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Proteins and Peptides

Recombinant Human Signaling Threshold Regulating Transmembrane Adaptor 1

Product Sizes
5 µg
£528.00
32-4854-5UG
About this Product
SKU:
32-4854
Additional Names:
Signaling threshold-regulating transmembrane adapter 1||SHP2-interacting transmembrane adapter protein||Suppression-inducing transmembrane adapter 1||gp30/40||SIT1||SIT||RP11-331F9.5||MGC125908||MGC125909||MGC125910.
Extra Details:
Source : Escherichia Coli. SIT1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 156 amino acids (62-196 a.a.) and having a molecular mass of 16.9kDa (Molecular weight on SDS-PAGE will appear higher).SIT1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Signaling threshold-regulating transmembrane adapter 1 (SIT1) negatively regulates T-cell antigen receptor (TCR)-mediated signaling in T-cells. SIT1 is involved in positive selection of T-cells. SIT1 is specifically expressed in T- and B-cells. SIT1 is also present in plasma cells but not in germinal center B-cells (at protein level). SIT1 is expressed in T- and B-cell lymphoma.
Purification:
Greater than 90.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
  • Manufacturer's Data Sheet:1.jpg