Recombinant Human Signal-Regulatory Protein Alpha
Product Sizes
20 µg
£528.00
32-4847-20UG
About this Product
- SKU:
- 32-4847
- Additional Names:
- Signal-Regulatory Protein Alpha||SHPS1||CD172 Antigen-Like Family Member A||Inhibitory Receptor SHPS-1||Macrophage Fusion Receptor||PTPNS1||SIRP||P84||BIT||MFR|| Brain-Immunoglobulin-Like Molecule With Tyrosine-Based Activation Motifs||Brain Ig-Like
- Extra Details:
- Source : Escherichia Coli. SIRPA Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 370 amino acids (27-373 a.a) and having a molecular mass of 40.4kDa. SIRPA is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Signal-Regulatory Protein Alpha; SIRPA belongs to the signal-regulatory-protein (SIRP) family; as well as the immunoglobulin super family. The members of the SIRP family are receptor-type transmembrane glycoproteins which are involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPA can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP); and perform as substrates of PTPs. SIRPA take part in signal transduction mediated by a variety of growth factor receptors. CD47 has been shown to be a ligand for SIRPA.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
