Recombinant Human SH3-domain GRB2-like 2
Product Sizes
20 µg
£528.00
32-4841-20UG
About this Product
- SKU:
- 32-4841
- Additional Names:
- Endophilin-A1||EEN-B1||Endophilin-1||SH3 domain protein 2A||SH3 domain-containing||GRB2-like protein 2||SH3GL2||CNSA2||SH3D2A||SH3P4.
- Extra Details:
- Source : Escherichia Coli. SH3GL2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 376 amino acids (1-352 a.a) and having a molecular mass of 42.5kDa.SH3GL2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. SH3-domain GRB2-like 2 (SH3GL2) is a member of the endophilin family. SH3GL2 contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are crucial elements of cellular traffic. Endophilins have a major function in synaptic vesicle endocytosis (SVE); receptor trafficking and apoptosis; and in other processes which require remodeling of the membrane structure. SH3GL2 is a novel tumor suppressor gene in laryngeal squamous cell carcinoma (LSCC); which induces apoptosis of tumor cells by regulating intra-cellular signal transduction networks. SH3GL2 is implicated in synaptic vesicle endocytosis. SH3GL2 is found in the brain; mainly in frontal cortex; and at high level in the fetal cerebellum.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
