Recombinant Human Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha
Product Sizes
25 µg
£528.00
32-4834-25UG
About this Product
- SKU:
- 32-4834
- Additional Names:
- alphaSGT||hSGT||SGT||Vpu-binding protein||UBP||Small glutamine-rich tetratricopeptide repeat-containing protein alpha||Alpha-SGT||SGT1.
- Extra Details:
- Source : Escherichia Coli. SGTA Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 321 amino acids (1-313 a.a.) and having a molecular mass of 35.1 kDa. SGTA protein is fused to a 8 amino acid His-Tag at C-terminus and purified by standard chromatography. SGTA is a ubiquitously expressed protein that contains three TPR protein-protein interaction duplicates. SGTA takes part as a component of the androgen receptor (AR)-chaperone-cochaperone complex; functions as a cochaperone and participates in androgen signaling. SGTA binds directly to HSC70 and HSP70 and mediates their ATPase activity. SGTA gene encodes a protein that is able to interact with the chief nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate. In addition; SGTA interacts with Vpu and Gag from HIV-1; SARS-CoV accessory protein 7a; DNAJC5 and DNAJC5B. Since this transcript is expressed universally in several tissues; SGTA serves a housekeeping function. While being involved in apoptosis and androgen signaling; SGTA is a possible molecule for polycystic ovary syndrome; a disorder characterized by androgen excess; obesity and menstrual disturbances.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- SGTA human although stable at 4[o]C for 1 week; should be stored desiccated below -18[o]C. Please prevent freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
