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Recombinant Human Surfactant Protein D

Product Sizes
20 µg
£528.00
32-4833-20UG
About this Product
SKU:
32-4833
Additional Names:
Surfactant Protein D||SFTP4||Surfactant Pulmonary-Associated Protein D||Lung Surfactant Protein D||Collectin-7||COLEC7||PSP-D||SP-D||Surfactant-Associated Protein Pulmonary 4||Pulmonary Surfactant-Associated Protein D||Pulmonary Surfactant Apoprotein
Extra Details:
Source : Escherichia Coli. SFTPD Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 175 amino acids (224-375 a.a) and having a molecular mass of 18.9kDa.SFTPD is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Surfactant pulmonary-associated protein D (SFTPD) belongs to the collectin family of C-type lectins; which is synthesized in many tissues including respiratory epithelial cells in the lung; and contains one C-type lectin domain and one collagen-like domain. SFTPD has humoral molecules of the innate immune system; and is deemed a functional candidate in chronic periodontitis. Moreover; SFTPD is involved in the development of acute and chronic inflammation of the lung. A number of human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. SFTPD contributes to the lungs defense against inhaled microorganisms; organic antigens and toxins. SFTPD interacts with complexes such as bacterial lipopolysaccharides; oligosaccharides and fatty acids and modulates leukocyte action in immune response. In addition; SFTPD participates in the extracellular reorganization or turnover of pulmonary surfactant. SFTPD binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Purification:
Greater than 80.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg