Recombinant Human Serpin Peptidase Inhibitor; Clade C Member 1
Product Sizes
20 µg
£528.00
32-4818-20UG
About this Product
- SKU:
- 32-4818
- Additional Names:
- AT3||AT3D||ATIII||THPH7||Antithrombin-III||Serpin C1||SERPINC1.
- Extra Details:
- Source : Escherichia Coli. SERPINC1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 455 amino acids (33-464 a.a) and having a molecular mass of 51.4kDa. SERPINC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Serpin Peptidase Inhibitor; Clade C Member 1 (SERPINC1); which is a part of the serpin superfamily; is a plasma protease inhibitor. SERPINC1 inhibits thrombin and other activated serine proteases of the coagulation system; and regulates the blood coagulation cascade. SERPINC1 also inhibits Thrombin and Factors IXa; Xa and XIa. The inhibitory activity of SERPINC1 is significantly enhanced in the presence of heparin. Deficiencies in SERPINC1 can cause ATIII deficiency; an autosomal dominant disease which might lead to a hereditary thrombophilia.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
