Recombinant Human SCO Cytochrome Oxidase Deficient Homolog 2
Product Sizes
10 µg
£528.00
32-4780-10UG
About this Product
- SKU:
- 32-4780
- Additional Names:
- SCO1L||SCO Cytochrome Oxidase Deficient Homolog 2 (yeast)||Protein SCO2 Homolog-Mitochondrial|| MGC125823||MGC125825.
- Extra Details:
- Source : Escherichia Coli. SCO2 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 246 amino acids (42-266a.a.) and having a molecular mass of 27.4kDa.SCO2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. SCO2 protein is a member of the SCO1/2 family. SCO1 and SCO2 proteins are found on the inner membrane of the mitochondria and takes a vital part copper insertion or transport to the active site of cytochrome c oxidase (COX). Flaws in SCO2 are the reason for deadly infantile cardioencephalomyopathy with cytochrome c oxidase deficiency (FIC) which is characterized by hypertrophic cardiomyopathy; lactic acidosis; and gliosis. Heart and skeletal muscle display declines in cytochrome c oxidase (COX) activity; while liver and fibroblasts show mild COX deficiencies.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
