Recombinant Human Regulator of G-Protein Signaling 1
Product Sizes
20 µg
£528.00
32-4641-20UG
About this Product
- SKU:
- 32-4641
- Additional Names:
- Regulator of G-protein signaling 1||RGS1||B-cell activation protein BL34||Early response protein 1R20||1R20||BL34||IER1||IR20.
- Extra Details:
- Source : Escherichia Coli. RGS1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 233 amino acids (1-209 a.a) and having a molecular mass of 26kDa.RGS1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. RGS1 belongs to the regulator of G-protein signaling family. The RGS1 protein is situated on the cytosolic side of the plasma membrane and contains a conserved; 120 amino acid motif termed the RGS domain. RGS1 diminish s the signaling activity of G-proteins by binding to activated; GTP-bound G alpha subunits and performing as a GTPase activating protein (GAP); boosting the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers; creating inactive G-protein heterotrimers; thus terminating the signal.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
