Recombinant Human Receptor Activity-Modifying Protein 1
Product Sizes
10 µg
£528.00
32-4595-10UG
About this Product
- SKU:
- 32-4595
- Additional Names:
- Receptor (G Protein-Coupled) Activity Modifying Protein 1||Receptor (Calcitonin) Activity Modifying Protein 1||Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1||CRLR Activity-Modifying Protein 1.
- Extra Details:
- Source : Escherichia Coli. RAMP1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 114 amino acids (27-117) and having a molecular mass of 12.9 kDa. RAMP1 is fused to a 23 amino acid His-tag at N-terminus. RAMP belongs to the type I transmembrane family of proteins called RAMP (receptor/calcitonin activity modifying proteins) which include an extracellular N terminus and a cytoplasmic C terminus. RAMPs are essential for CRLR transport to the plasma membrane. CRLR (calcitonin-receptor-like receptor) has seven transmembrane domains. Depending on which members of the RAMP family are expressed CRLR receptor functions as either an adrenomedullin receptor or a calcitonin-gene-related peptide (CGRP) receptor. In the presence of RAMP1; CRLR functions as a CGRP receptor. The RAMP1 protein takes part in the terminal glycosylation; maturation; and presentation of the CGRP receptor to the cell surface.
- Purification:
- Greater than 80% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
