Recombinant Human RAB32; Member RAS Oncogene Family
Product Sizes
20 µg
£528.00
32-4564-20UG
About this Product
- SKU:
- 32-4564
- Additional Names:
- RAB32 member RAS oncogene family||ras-related protein Rab-32.
- Extra Details:
- Source : E.coli. RAB32 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 249 amino acids (1-225) and having a molecular mass of 27.6 kDa.RAB32 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. RAB32 is a member of the small GTPase superfamily. RAB32 controls ER calcium management and disturbs the specific enhancement of calnexin on the MAM (mitochondria-associated membrane); however avoids affecting the ER distribution of protein-disulfide isomerase and mitofusin-2. Furthermore; RAB32 regulates the targeting of PKA (cAMP-dependent protein kinase) to mitochondrial and ER membranes and by inactivation or overexpression enhances the phosphorylation of Drp1 and Bad. Using a combination of its functions as a regulator of MAM properties and a PKA-anchoring protein; the activity and expression level of RAB32 define the speed of apoptosis onset.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
