Recombinant Human Proteasome Activator Subunit 3
Product Sizes
10 µg
£528.00
32-4529-10UG
About this Product
- SKU:
- 32-4529
- Additional Names:
- Proteasome (prosome||macropain) activator subunit 3 (PA28 gamma; Ki)||PA28G||Ki||Ki nuclear autoantigen||PA28-gamma||REG-GAMMA||Activator of multicatalytic protease subunit 3||Proteasome activator 28 subunit gamma||11S regulator complex subunit gamma
- Extra Details:
- Source : E.coli. PSME3 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 274 amino acids (1-254 a.a.) and having a molecular mass of 31.7kDa. PSME3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PSME3 is a member of the PA28 family. The 26S proteasome is an extremely organized multicatalytic proteinase complex composed of 2 complexes; a 20S core and a 19S regulator. Proteasomes are spread all over the eukaryotic cells in large quantities and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSME3 stimulates the trypsin-like catalytic subunit of the proteasome and inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSEM3 enables the MDM2-p53/TP53 collaboration that encourages ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53; restricting its growth and causing inhibited apoptosis after DNA damage.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
