Recombinant Human Proteasome Beta Type 10
Product Sizes
5 µg
£528.00
32-4526-5UG
About this Product
- SKU:
- 32-4526
- Additional Names:
- Proteasome subunit beta type-10||Low molecular mass protein 10||Macropain subunit MECl-1||Multicatalytic endopeptidase complex subunit MECl-1||Proteasome MECl-1||Proteasome subunit beta-2i||PSMB10||LMP10||MECL1||beta2i||MGC1665||FLJ00366.
- Extra Details:
- Source : Escherichia Coli. PSMB10 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 255 amino acids (40-273 a.a.) and having a molecular mass of 26.9kDa.PSMB10 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PSMB10 is a member of the proteasome B-type family (T1B family) which is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with an extremely ordered ring-shaped 20S core structure. This core structure is comprised of four rings of 28 non-identical subunits; two rings are composed of seven alpha subunits and two rings are composed of seven beta subunits. Proteasomes are circulated in eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. A crucial function of a modified proteasome; the immunoproteasome; is the processing of class I MHC peptides. PSMB10 gene expression is induced by interferon-gamma; and it replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
