Recombinant Human Prosaposin
Product Sizes
10 µg
£528.00
32-4505-10UG
About this Product
- SKU:
- 32-4505
- Additional Names:
- Prosaposin||Proactivator polypeptide||PSAP||GLBA||SAP1.
- Extra Details:
- Source : HEK 293. PSAP Human Recombinant produced in HEK cells is a single; glycosylated; polypeptide chain (a.a 17-524) containing a total of 518 amino acids; having a molecular mass of 57.7kDa (calculated); though it migrates at approximately 65kDa on SDS PAGE; the PSAP is fused to a 2 a.a N-terminal linker; a 2 a.a C-terminal linker and a 6 a.a His tag at C-Terminus.The Human PSAP is purified by proprietary chromatographic techniques. Prosaposin (PSAP) is a precursor of 4 lysosomal saposin proteins (saposin A; B; C and D). Saposins are heat-stable glycoproteins which facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. PSAP stimulates neurite outgrowth and increases choline acetyltransferase activity. Prosaposin exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. The secreted prosaposin is assumed to have additional functions in human milk; cerebrospinal fluid and seminal plasma. PSAP gene mutations are linked with Gaucher disease; Tay-Sachs disease; and metachromatic leukodystrophy.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
