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Proteins and Peptides

Recombinant Human Proopiomelanocortin

Product Sizes
10 µg
£528.00
32-4482-10UG
About this Product
SKU:
32-4482
Additional Names:
Pro-opiomelanocortin||POMC||Corticotropin-lipotropin||LPH||MSH||NPP||POC||ACTH||CLIP.
Extra Details:
Source : Escherichia Coli. POMC produced in E.Coli is a single; non-glycosylated polypeptide chain containing 262 amino acids (27-267 a.a) and having a molecular mass of 28.9kDa (molecular weight on SDS-PAGE will appear higher).POMC is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Pro-opiomelanocortin preproprotein (POMC) is a polypeptide hormone precursor which experiences extensive; tissue-specific; post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. POMC regulates the corticosteroid production in the adrenal cortex. Furthermore; POMC is cleaved into ten hormone chains named NPP; g-MSH; ACTH; a-MSH; CLIP; Lipotropin b; Lipotropin g; b-MSH;b endorphin and Met-enkephalin. POMC gene defects are the cause of POMC deficiency; which is characterized by red hair and adrenal insufficiency.
Purification:
Greater than 85.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
  • Manufacturer's Data Sheet:1.jpg