Recombinant Human Phospholipid Scramblase 3
Product Sizes
25 µg
£528.00
32-4468-25UG
About this Product
- SKU:
- 32-4468
- Additional Names:
- Phospholipid scramblase 3||PL scramblase 3||Ca(2+)-dependent phospholipid scramblase 3.
- Extra Details:
- Source : Escherichia Coli. PLSCR3 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 288 amino acids (1-265 a.a) and having a molecular mass of 30.9kDa.PLSCR3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Phospholipid Scramblase 3; (PLSCR3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions which results in a loss of phospholipid asymmetry in the plasma membrane. PLSCR3 may play a key role in the initiation of fibrin clot formation; in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. In addition; PLSCR3 seems to play a role in apoptosis; through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. Among the diseases associated with PLSCR3 are brain ischemia; and ischemia.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
