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Proteins and Peptides

Recombinant Human Proliferating Cell Antigen; S9

Product Sizes
20 µg
£528.00
32-4409-20UG
About this Product
SKU:
32-4409
Additional Names:
Proliferating cell nuclear antigen||PCNA||Cyclin||MGC8367.
Extra Details:
Source : Sf9 insect cells.  PCNA Human Recombinant produced in SF9 is a glycosylated; polypeptide chain having a molecular mass of 35 kDa. PCNA is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.  Proliferating cell nuclear antigen (PCNA); a protein of 30 kDa molecular weight also known as cyclin; forms a trimer ring around a DNA double-helix. It binds to a variety of other nuclear proteins and thereby organises biochemical processes at the DNA replication fork. PCNA thereby assumes important functions in DNA synthesis; repair and processing; the regulation of cell cycle and even apoptosis.Anti-PCNA antibodies occur in systemic lupus; where they represent a rare specificity (< 10 % of SLE patients). However; their presence alone or in combination with other autoantibodies should alert the clinician to the presence of defined or evolving SLE.
Purification:
Greater than 95% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
  • Manufacturer's Data Sheet:1.jpg