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Proteins and Peptides

Recombinant Human Proliferating Cell Antigen

Product Sizes
25 µg
£528.00
32-4407-25UG
About this Product
SKU:
32-4407
Additional Names:
Proliferating cell nuclear antigen||PCNA||Cyclin||MGC8367.
Extra Details:
Source : Escherichia Coli. PCNA Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 261 amino acids and having a molecular mass of 28769 Dalton. PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage; PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase; S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation.
Purification:
Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
  • Manufacturer's Data Sheet:1.jpg