Recombinant Human Nucleopurin 62kDa
Product Sizes
20 µg
£528.00
32-4357-20UG
About this Product
- SKU:
- 32-4357
- Additional Names:
- Nuclear pore glycoprotein p62||62 kDa nucleoporin||Nucleoporin Nup62||NUP62||p62||IBSN||SNDI.
- Extra Details:
- Source : Sf9 insect cells. NUP62 Human Recombinant produced in SF9 is a glycosylated; polypeptide chain having a calculated molecular mass of 54;626 Dalton. NUP62 is expressed with a -10x His tag at N-terminus and purified by proprietary chromatographic techniques. Nucleopurin 62kDa (NUP62) belongs to the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. Nucleoporins are the principal components of the nuclear pore complex in eukaryotic cells. This complex is a colossal structure which extends across the nuclear envelope; forming an entryway that regulates the stream of macromolecules between the nucleus and the cytoplasm. NUP62 associates with the importin alpha/beta complex that is involved in the import of proteins containing nuclear localization signals. Defects in the NUP62 are the cause of SNDI (infantile striatonigral degeneration); aka infantile bilateral striatal necrosis (IBSN) or familial striatal degeneration.
- Purification:
- Greater than 80% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
