Recombinant Human NmrA-Like Family Domain Containing 1
Product Sizes
20 µg
£528.00
32-4333-20UG
About this Product
- SKU:
- 32-4333
- Additional Names:
- NmrA-like family domain containing protein 1||short chain dehydrogenase/reductase family 48A member 1||HSCARG||SDR48A1||FLJ25918.
- Extra Details:
- Source : E.coli. NMRAL1 Human Recombinant produced in E. coli is a single polypeptide chain containing 323 amino acids (1-299) and having a molecular mass of 35.9 kDa.NMRAL1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. NMRAL1 is a redox sensor protein which goes through reformation and subcellular rearrangement in reaction to alterations in intracellular NADPH/NADP+ levels. When the NADPH concentration is low the protein is found mostly as a monomer; and binds argininosuccinate synthase (ASS1); which takes part in nitric oxide synthesis. Association with ASS1 defects NMRAL1 activity and diminishes the production of nitric oxide; which then inhibits apoptosis. When the NADPH concentration is normal ; the protein is found as a dimer and hides the binding site for ASS1.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
