Recombinant Human NK3 Homeobox 1
Product Sizes
20 µg
£528.00
32-4326-20UG
About this Product
- SKU:
- 32-4326
- Additional Names:
- Homeobox protein Nkx-3.1||Homeobox protein NK-3 homolog A||NKX3-1||NKX3.1||NKX3A||NKX3||BAPX2.
- Extra Details:
- Source : Escherichia Coli. NKX3-1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 257 amino acids (1-234 a.a) and having a molecular mass of 28.7kDa.NKX3-1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. NK3 Homeobox1 (NKX3-1) is a homeobox-containing transcription factor; which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and may act as a transcriptional repressor. The NKX3-1 transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. NKX3-1 has an imperative role in normal prostate development; regulating proliferation of glandular epithelium and in the formation of ducts in prostate. In addition; NKX3-1 functions as a tumor suppressor controlling prostate carcinogenesis; as shown by its ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. Abnormal expression of NKX3-1 is linked with prostate tumor progression.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
