Recombinant Human Nonhomologous End-Joining Factor 1
Product Sizes
10 µg
£528.00
32-4316-10UG
About this Product
- SKU:
- 32-4316
- Additional Names:
- Nonhomologous end-joining factor 1||Protein cernunnos||XRCC4-like factor||Cernunnos||XLF||FLJ12610.
- Extra Details:
- Source : E.coli. NHEJ1 Human Recombinant produced in E. coli is a single polypeptide chain containing 247 amino acids (1-224) and having a molecular mass of 27.8 kDa.NHEJ1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Non-homologous end-joining factor 1 (NHEJ1) is a member of the XLF family. NHEJ1 is a DNA repair factor vital for the nonhomologous end-joining pathway; which preferentially mediates repair of double-stranded breaks. NHEJ1 gene mutations cause different kinds of severe combined immunodeficiency disorders. NHEJ1 was initially detected as the protein mutated in five patients with growth retardation; microcephaly; and immunodeficiency. In addition; patients with NHEJ1 mutations have immunodeficiency caused by a defect in V(D)J recombination; which employs NHEJ to promote immune system diversity.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
