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Recombinant Human Myelin Protein Zero-Like 1

Product Sizes
10 µg
£528.00
32-4231-10UG
About this Product
SKU:
32-4231
Additional Names:
Myelin Protein Zero-Like 1||PZRa||PZR||Protein Zero-Related||PZRb||Immunoglobulin Family Transmembrane Protein||Myelin Protein Zero-Like Protein 1||MPZL1b||Protein Zero Related||PZR1b.
Extra Details:
Source : Escherichia Coli. MPZL1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 148 amino acids (38-162) and having a molecular mass of 16.1kDa.MPZL1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Myelin Protein Zero-Like 1 (MPZL1) is a cell surface receptor; which is involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. MPZL1 is a main receptor for concanavalin-A (ConA) and it is involved in cellular signaling induced by ConA; which most likely includes Src family tyrosine-protein kinases. MPZL1 Isoform 3 appears to have a dominant negative role by blocking tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1; but not isoform 2 and isoform 3; might be involved in regulation of integrin-mediated cell motility.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg