Myelin Oligodendrocyte Glycoprotein
Product Sizes
25 mg
£995.00
32-4225-25MG
About this Product
- SKU:
- 32-4225
- Additional Names:
- Myelin Oligodendrocyte Glycoprotein||MOG.
- Extra Details:
- Source : Myelin Oligodendrocyte Glycoprotein is a single; non-glycosylated polypeptide chain containing 21 amino acids and having a molecular mass of 2582 Dalton; the molecular formula: C118H177N35O29S. MOG is a transmembrane protein expressed on the surface of oligodendrocyte cell and on the outermost surface of myelin sheaths. MOG comprises about 0.1% of total CNS myelin protein. The MOG gene is a member of the immunoglobulin gene superfamily and is found within the MHC. The MOG gene is found on chromosome 6p21.3-p22. Myelin Oligodendrocyte Glycoprotein is a glycoprotein thought to be significant in the process of myelinization of nerves in the central nervous system (CNS). MOG peptide (35-55) is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing- remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical; histophathologic; and immunologic similarities with multiple sclerosis (MS); the MOG induced demyelinating encephalomyelitis may serve as a model for investigating MS.
- Purification:
- Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized MOG although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution MOG should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
