Recombinant Human Met Proto-Oncogene
Product Sizes
10 µg
£528.00
32-4202-10UG
About this Product
- SKU:
- 32-4202
- Additional Names:
- Hepatocyte growth factor receptor||HGF receptor||HGF/SF receptor||Proto-oncogene c-Met||Scatter factor receptor||SF receptor||Tyrosine-protein kinase Met||MET;HGFR||AUTS9||RCCP2.
- Extra Details:
- Source : Insect cells. Met Proto-Oncogene Human Recombinant produced in Insect cells amino acids 1039-1345; having a molecular weight of 34.6kDa.c-MET is purified by proprietary chromatographic techniques. Mesenchymal epithelial transition factor (c-MET) is a proto-oncogenic receptor tyrosine kinase. The endogenous ligand for c-MET is HGF (hepatocyte growth factor); which is a disulfide-linked heterodimeric molecule produced predominantly by mesenchymal cells. In the adult; c-MET protein expression is limited to stem and progenitor cells and is required for wound healing and hepatocyte regeneration. In the embryo; c-MET receptors are expressed on cells of epithelial origin; which are vital for invasive growth and mediate epithelial-mesenchymal transition (EMT). Abnormal activation of the HGF/MET pathway leads to a variety of cancers. c-MET mutation is linked with a poor prognosis since it can trigger tumor growth; angiogenesis and metastasis.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
