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Proteins and Peptides

Recombinant Human Mediator Complex Subunit 27

Product Sizes
10 µg
£528.00
32-4195-10UG
About this Product
SKU:
32-4195
Additional Names:
Mediator Complex Subunit 27||MED27||CRSP8||Cofactor Required For Sp1 Transcriptional Activation||Subunit 8 34kDa||P37 TRAP/SMCC/PC2 Subunit||Transcriptional Coactivator CRSP34||CRSP34||CRSP Complex Subunit 8||CRAP34||TRAP37||Mediator of RNA Polymeras
Extra Details:
Source : E.coli. MED27 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 334 amino acids (1-311) and having a molecular mass of 37.8 kDa.MED27 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Mediator Complex Subunit 27 (MED27) is a subunit of the CRSP (cofactor required for SP1 activation) complex; which; together with TFIID; is necessary for efficient activation by SP1. MED27 is a component of the Mediator complex; a coactivator involved in the regulated transcription of virtually all RNA polymerase II-dependent genes. MED27 protein is also a component of other multisubunit complexes such as the thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. The activation of MED27 gene transcription is a multistep process; which is triggered by factors that identify transcriptional enhancer sites in DNA.
Purification:
Greater than 80% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
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