Recombinant Human Mediator Complex Subunit 4
Product Sizes
25 µg
£528.00
32-4192-25UG
About this Product
- SKU:
- 32-4192
- Additional Names:
- Mediator of RNA polymerase II transcription subunit 4||Mediator complex subunit 4||Vitamin D3 receptor-interacting protein complex 36 kDa component||Activator-recruited cofactor 36 kDa component||TRAP/SMCC/PC2 subunit p36 subunit||DRIP36||ARC36||MED4
- Extra Details:
- Source : Escherichia Coli. MED4 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 278 amino acids (1-270 a.a.) and having a molecular mass of 30.7kDa. MED4 is fused to 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques. Mediator complex subunit 4 (MED4) is a component of the Mediator complex; a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED4 is a component of the vitamin D receptor-interacting protein (DRIP) complex which functions as a nuclear receptor coactivator. The DRIP complex is able to activate nuclear receptors in a ligand-dependent manner. MED4 functions as a link to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription apparatus. MED4 is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
- Purification:
- Greater than 80.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
