Recombinant Human Malignant T-Cell-Amplified Sequence 1
Product Sizes
20 µg
£528.00
32-4188-20UG
About this Product
- SKU:
- 32-4188
- Additional Names:
- MCT-1||MCT1||Malignant T-cell-amplified sequence 1||Multiple copies T-cell malignancies.
- Extra Details:
- Source : E.coli. MCTF1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 204 amino acids (1-181 a.a.) and having a molecular mass of 22.9kDa. MCTF1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Malignant T cell amplified sequence 1 (MCTS1) is an Anti-oncogene which takes part in cell cycle regulation by means of decreasing cell doubling time and encouraging-dependent growth and also by shorting the duration of G1 transit time and G1/S transition. MCTS1 also plays a role as translation enhancer. MCTS1 recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs; thereupon altering the mRNA translation profile; Up-regulates protein levels of BCL2L2; TFDP1; MRE11A; CCND1 and E2F1; while mRNA levels remains constant.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
