Recombinant Human Melanoma Antigen Family A; 6
Product Sizes
10 µg
£528.00
32-4159-10UG
About this Product
- SKU:
- 32-4159
- Additional Names:
- Melanoma-associated antigen 6||Cancer/testis antigen 1.6||CT1.6||MAGE-6 antigen||MAGE3B antigen||MAGEA6||MAGE6||MAGE3B||MAGE-3b.
- Extra Details:
- Source : E.coli. MAGEA6 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 322 amino acids (1-314 a.a) and having a molecular mass of 35.9kDa.MAGEA6 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. MAGEA6 belongs to the MAGEA family; which directs the expression of tumor antigens which are seen on a human melanoma by autologous cytolytic T lymphocytes (CTL). Members of the MAGEA family encode proteins with 50 to 80% sequence identity to each other. The MAGE genes; which are clustered at chromosomal location Xq28; were originally isolated from separate kinds of tumors; and based on their practically exclusive tumor-specific expression in adult tissues; they are objects for cancer immunotherapy. MAGEA genes' promoters and first exons exhibit substantial variability; implying that the existence of the MAGEA gene family enables the same function to be expressed under different transcriptional controls. MAGEA genes are implicated in several hereditary disorders; such as dyskeratosis congenita.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
