Recombinant Human Mannose-6-Phosphate Receptor
Product Sizes
10 µg
£528.00
32-4144-10UG
About this Product
- SKU:
- 32-4144
- Additional Names:
- Mannose-6-Phosphate Receptor (Cation Dependent)||CD-MPR||MPR46||CD Man-6-P Receptor||MPR 46||46-KDa Mannose 6-Phosphate Receptor||MPR-46||SMPR||Cation-Dependent Mannose-6-Phosphate Receptor||Mr 46;000 Man6PR||Small Mannose 6-Phosphate Receptor||46 KD
- Extra Details:
- Source : Escherichia Coli. M6PR Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 182 amino acids (27-185) and having a molecular mass of 20.3kDa.M6PR is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Mannose-6-Phosphate Receptor (M6PR) belongs to the P-type lectin family. P-type lectins play a vital role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The M6PR protein functions as a homodimer and needs divalent cations for ligand binding. Lysosomal enzymes carrying phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the ensuing receptor-ligand complex is transferred to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
