Recombinant Human LIN28
Product Sizes
10 µg
£528.00
32-4112-10UG
About this Product
- SKU:
- 32-4112
- Additional Names:
- CSDD1||FLJ12457||LIN-28||LIN28A||Protein lin-28 homolog A||ZCCHC1||Zinc finger CCHC domain-containing protein 1||Lin-28A||LIN28.
- Extra Details:
- Source : Escherichia Coli. Recombinant Human LIN28 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 191 amino acids (42-209) and having a molecular mass of 21.1 kDa.LIN28 is expressed with a 23 amino acid His tag fused at N-Terminus and purified by proprietary chromatographic techniques. LIN28 plays an important role as a 'translational enhancer'; leading specific mRNAs to polysomes and therefore increasing the competence of protein synthesis. LIN28 is a marker of undifferentiated human embryonic stem cells and it enhances the efficiency of the formation of induced pluripotent stem (iPS) cells from human fibroblasts. LIN28 binds to the let-7 pre-miRNA and blocks production of the mature let-7 microRNA in mouse embryonic stem cells. Overexpression of LIN28 is associated with human germ-cell tumors.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
