Recombinant Human LAMTOR4
Product Sizes
10 µg
£528.00
32-4092-10UG
About this Product
- SKU:
- 32-4092
- Additional Names:
- Late Endosomal/Lysosomal Adaptor||MAPK And MTOR Activator 4||C7orf59||Late Endosomal/Lysosomal Adaptor And MAPK And MTOR Activator 4||Chromosome 7 Open Reading Frame 59||Ragulator Complex Protein LAMTOR4||UPF0539 Protein C7orf59||LAMTOR4.
- Extra Details:
- Source : Escherichia Coli. LAMTOR4 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 122 amino acids (1-99 a.a) and having a molecular mass of 13.1kDa. LAMTOR4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. LAMTOR4 is implicated in amino acid sensing and activation of mTORC1; which is a signaling complex promoting cell growth in response to growth factors; energy levels; and amino acids. LAMTOR4 is activated by amino acids via a mechanism which involves the lysosomal V-ATPase; the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases both function as a scaffold recruiting mTORC1 to lysosomes where it is sequentially activated.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
