Recombinant Human Lamin-A
Product Sizes
10 µg
£528.00
32-4089-10UG
About this Product
- SKU:
- 32-4089
- Additional Names:
- Prelamin-A/C||LMNA||LMN1||Lamin-A/C||70 kDa lamin||Renal carcinoma antigen NY-REN-32||FPL||IDC||LFP||CDDC||EMD2||FPLD||HGPS||LDP1||LMNC||PRO1||CDCD1||CMD1A||FPLD2||LMNL1||CMT2B1||LGMD1B.
- Extra Details:
- Source : Escherichia Coli. Recombinant Human Lamin A produced in E.Coli is a single; non-glycosylated polypeptide chain containing 645 amino acids and having a molecular mass of 70 kDa. Lamin-A is a major component of the nuclear lamina; a dynamic meshwork located just under the nuclear envelope and it is encoded by lamin A/C gene (LMNA).Lamin-A is synthesized as Prelamin A; a longer precursor that in vivo goes through a serial post-translational modifications that lead to mature Lamin A.Diverse mutations in the Lamin A/C gene are associated with different diseases that are collectively called laminophaties; including Emery-Dreifuss muscular dystrophy; familiar partial lipodystrophy; limb girdle muscular dystrophy; dilated cardiomyopathy; Charcot-Marie-Tooth disease; and Hutchinson-Gilford progeria syndrome.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
