Recombinant Human Leukocyte-Associated Ig-Like Receptor 2
Product Sizes
20 µg
£528.00
32-4088-20UG
About this Product
- SKU:
- 32-4088
- Additional Names:
- Leukocyte-associated immunoglobulin-like receptor 2||LAIR-2||CD306||LAIR2.
- Extra Details:
- Source : Escherichia Coli. LAIR2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 139 amino acids (22-135 a.a) and having a molecular mass of 15.2kDa.LAIR2 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) is a secreted; 131 amino acids protein which contains one IglikeC2 type domain; rendering it a member of the Ig superfamily. Even though one is secreted and one is membrane bound; the 2 LAIR proteins are assumed to have evolved from a common gene ancestor and seem to share similar adhesion profiles; suggesting that LAIR2 may compete with LAIR1 for ligand binding. LAIR2 was discovered by its similarity to LAIR1; which is an inhibitory receptor present on mononuclear leukocytes. The LAIR2 gene maps to a region of 19q13.4; dubbed the leukocyte receptor cluster; which contains 29 genes in the immunoglobulin superfamily; including LAIR1. The function of the LAIR2 protein is unknown; though it is assumed to be secreted and may help modulate mucosal tolerance.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
