Recombinant Human Killer Cell lectin-Like Receptor Subfamily K; Member 1
Product Sizes
20 µg
£528.00
32-4064-20UG
About this Product
- SKU:
- 32-4064
- Additional Names:
- CD314||D12S2489E||KLR||NKG2-D||NKG2D||Killer cell lectin-like receptor subfamily K member 1||NK cell receptor D||NKG2-D-activating NK receptor||CD314.
- Extra Details:
- Source : Escherichia Coli. KLRK1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 168 amino acids (73-216 a.a.) and having a molecular mass of 19.2kDa. KLRK1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Killer Cell lectin-Like Receptor Subfamily K; Member 1 (KLRK1) is an activating receptor which has recently generated considerable interest. The most fascinating of these; are a couple of closely related proteins known as MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins; and their genes have elements of heat shock promoters. Thus; MICA and MICB are expressed in the course of cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination has a crucial role in the immune response to various pathologies.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
