Recombinant Human Immunity-Related GTPase Family; M
Product Sizes
20 µg
£528.00
32-4024-20UG
About this Product
- SKU:
- 32-4024
- Additional Names:
- Immunity-related GTPase family M protein||Immunity-related GTPase family M protein1||Interferon-inducible protein 1||LPS-stimulated RAW 264.7 macrophage protein 47 homolog||LRG-47||IRGM||IFI1||IRGM1||LRG47.
- Extra Details:
- Source : Escherichia Coli. IRGM Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 180 amino acids (23-181) and having a molecular mass of 20.1 kDa. IRGM is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Immunity-related GTPase family M protein (IRGM) is essential for clearance of severe protozoan and bacterial infections. IRGM belongs to the p47 immunity-related GTPase family. IRGM serves in innate immune response possibly via regulation of autophagy. IRGM regulates proinflammatory cytokine production and inhibit endotoxemia upon infection and also has a part in macrophages adhesion and motility. Polymorphisms which modify the natural expression of the IRGM gene are associated with a susceptibility to Crohn's disease and tuberculosis.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:1.jpg
