HUS1 Recombinant Protein
Product Sizes
5 µg
£528.00
32-3999-5UG
About this Product
- SKU:
- 32-3999
- Additional Names:
- HUS1 Checkpoint Homolog (S. pombe)||Checkpoint Protein HUS1||Hus1+-like protein.
- Extra Details:
- Source : Escherichia Coli. HUS1 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 300 amino acids (1-280a.a.) and having a molecular mass of 33.8kDa.HUS1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. HUS1 is a component of an evolutionarily conserved; genotoxin-activated checkpoint complex. HUS1 protein connects with Rad9 and Rad1 to form the 9-1-1(RAD9-RAD1-HUS1) complex; that confines to DNA lesions and promotes DNA damage signaling and repair or apoptosis; cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
