HOXA9 Recombinant Protein
Product Sizes
20 µg
£528.00
32-3989-20UG
About this Product
- SKU:
- 32-3989
- Additional Names:
- Homeobox A9||HOX1G||Homeobox Protein Hox-1G||Homeodomain Protein HOXA9||Homeobox Protein Hox-A9||Homeo Box A9||HOX1.7||ABD-B||HOX1||HOXA9.
- Extra Details:
- Source : Escherichia Coli. HOXA9 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 295 amino acids (1-272) and having a molecular mass of 32.6 kDa.HOXA9 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Homeobox A9 (HOXA9) is a member of the Abd-B homeobox family. The HOXA9 protein is a transcription factor with a key role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a distinctive feature of acute myeloid leukaemia (AML); and may be sufficient to cause this disease. HOXA9 overexpression noticeably expands hematopoietic stem cells. The HOXA9 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which regulates gene expression; morphogenesis; and differentiation. HOXA9 is a sequence-specific transcription factor which is part of a developmental regulatory system; which provides cells with specific positional identities on the anterior-posterior axis. HOXA9 is essential for induction of E-selectin and VCAM-1; on the endothelial cells surface at sites of inflammation.
- Purification:
- "Greater than 85.0% as determined by SDS-PAGE."
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
