HOPX Recombinant Protein
Product Sizes
20 µg
£528.00
32-3988-20UG
About this Product
- SKU:
- 32-3988
- Additional Names:
- Homeodomain-only protein||Lung cancer-associated Y protein||Not expressed in choriocarcinoma protein 1||Odd homeobox protein 1||HOPX||HOD||HOP||LAGY||NECC1||OB1||TOTO||CAMEO||SMAP31.
- Extra Details:
- Source : Escherichia Coli. HOPX Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 97 amino acids (1-73 a.a) and having a molecular mass of 10.8kDa.HOPX is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Homeodomain-only protein (HOPX) functions via its interaction with SRF; thus modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. HOPX inhibits SRF-dependent transcription either by hindering SRF binding to DNA or by engaging histone deacetylase (HDAC) proteins which prevent transcription by SRF. HOPX is a homeodomain protein which lacks certain conserved residues required for DNA binding. HOPX overexpression causes cardiac hypertrophy.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
