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HLA-DRB1 Recombinant Protein

Product Sizes
20 µg
£528.00
32-3967-20UG
About this Product
SKU:
32-3967
Additional Names:
DRB1||HLA DRB1||HLA-DR1B||HLA-DRB1||MHC class II antigen DRB1 16||DR-16||DR16||Human Leucocyte AntigenDRB1||MHC Class IIHLA-DR-Beta Cell Surface Glycoprotein||MHC Class IIHLA-DRw10-Beta.
Extra Details:
Source : Escherichia Coli. HLA-DRB1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 219 amino acids (30-227 a.a) and having a molecular mass of 25.2kDa.HLA-DRB1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Major Histocompatibility Complex Class II DR Beta 1 also known as HLA-DRB1 ia a member of the HLA class II beta chain paralogs. Molecule class II is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB); both anchored in the membrane. HLA-DRB1 takes an essential part in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). Furthermore; the beta chain is approximately 26- 28 kDa. It is encoded by 6 exons. While exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail.
Purification:
"Greaterthan 85% as determined by SDS-PAGE."
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg